Details for gene set HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION[GSEA]

Table: GSEA Results Summary

Dataset	set03_wtNotch_versus_absentNotch
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION
Enrichment Score (ES)	0.53858984
Normalized Enrichment Score (NES)	1.7464826
Nominal p-value	0.0038910506
FDR q-value	0.4546628
FWER p-Value	0.896

Fig 1: Enrichment plot: HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ALDOA	295	2.455	0.1004	Yes
2	GNE	716	1.994	0.1723	Yes
3	GNPDA1	1015	1.809	0.2419	Yes
4	ENO3	1236	1.698	0.3105	Yes
5	NPL	1445	1.614	0.3758	Yes
6	PFKP	1820	1.467	0.4251	Yes
7	PGAM1	1979	1.405	0.4832	Yes
8	PGK1	2200	1.329	0.5343	Yes
9	PFKM	3081	1.090	0.5386	Yes
10	PKM2	6082	0.506	0.4012	No
11	PGK2	6126	0.500	0.4226	No
12	GNPDA2	6460	0.446	0.4258	No
13	ENO2	6765	0.396	0.4282	No
14	BPGM	6959	0.364	0.4351	No
15	ENO1	7758	0.241	0.4035	No
16	PGAM2	8198	0.176	0.3883	No
17	GAPDHS	8823	0.074	0.3582	No
18	PFKL	10414	-0.175	0.2810	No
19	ALDOB	11027	-0.272	0.2609	No
20	TPI1	13273	-0.607	0.1690	No
21	PKLR	15303	-0.994	0.1069	No
22	ALDOC	17167	-1.503	0.0779	No

Fig 2: HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION: Random ES distribution
Gene set null distribution of ES for HUMANCYC_SUPERPATHWAY OF N-ACETYLNEURAMINATE DEGRADATION